Determination of Neutron Flux in Brain Cancer Boron Neutron Capture Therapy Using Monte Carlo Simulation

نویسندگان

چکیده

Boron Neutron Capture Therapy (BNCT) is a relatively safer technology for killing cancer cells, one of which the Glioblastoma multiforme. One main components BNCT equipment collimator functions as an exit point epithermal neutron particles that hit cells. In addition to experimental method, research can be carried out by modeling, including using MCNPX software based on Monte Carlo Method. This aimed determine flux distribution fast and neutrons dose rate gamma target cells in phantom head ORNL MIRD. Modeling has three parts: cell cards, surface data cards. A tally used card calculate flux. Based calculation modeling results, 2.87 x 109 n/cm2.s. The ratio 2.29 10-14 Gy.cm2/n. Then, balance 1.64 Gy.cm2/n, thermal 0.004. this study, hitting was moderated at 4 cm so depth 8 cm, energy converted into neutrons. analysis it concluded will interact with tissue neutrons, not

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Design and Simulation of Photoneutron Source by MCNPX Monte Carlo Code for Boron Neutron Capture Therapy

Introduction Electron linear accelerator (LINAC) can be used for neutron production in Boron Neutron Capture Therapy (BNCT). BNCT is an external radiotherapeutic method for the treatment of some cancers. In this study, Varian 2300 C/D LINAC was simulated as an electron accelerator-based photoneutron source to provide a suitable neutron flux for BNCT. Materials and Methods Photoneutron sources w...

متن کامل

A Monte Carlo study of SPECT in boron neutron capture therapy for a heterogeneous human phantom

Background: Boron neutron capture therapy (BNCT) is a binary radiotherapy combining biochemical targeting with neutron irradiation. However, monitoring the boron distribution is a fundamental problem in BNCT. Prompt gamma rays emitted by boron capture reaction can be used to address the issue. Materials and Methods: The general-purpose Monte Carlo toolkits Geant4 and MCNP were used for the simu...

متن کامل

design and simulation of photoneutron source by mcnpx monte carlo code for boron neutron capture therapy

introduction electron linear accelerator (linac) can be used for neutron production in boron neutron capture therapy (bnct). bnct is an external radiotherapeutic method for the treatment of some cancers. in this study, varian 2300 c/d linac was simulated as an electron accelerator-based photoneutron source to provide a suitable neutron flux for bnct. materials and methods photoneutron sources w...

متن کامل

Design and Simulation of Photoneutron Source by MCNPX Monte Carlo Code for Boron Neutron Capture Therapy

Introduction Electron linear accelerator (LINAC) can be used for neutron production in Boron Neutron Capture Therapy (BNCT). BNCT is an external radiotherapeutic method for the treatment of some cancers. In this study, Varian 2300 C/D LINAC was simulated as an electron accelerator-based photoneutron source to provide a suitable neutron flux for BNCT. Materials and Methods Photoneutron sources w...

متن کامل

Boron Neutron Capture Therapy

A project aimed at the development of an accelerator facility devoted to Boron Neutron Capture Therapy (BNCT) is ongoing at the National Atomic Energy Commission of Argentina [1]. In a first stage of development, the accelerator will be capable of delivering proton or deuteron beams of 30 mA at about 1.4 MeV which is suitable for neutron production through the 9Be(d,n) reaction. In this context...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Physics communication

سال: 2022

ISSN: ['2528-5971', '2528-598X']

DOI: https://doi.org/10.15294/physcomm.v6i2.40277